“Our genes load the gun, but our environment pulls the trigger.”
Have you heard this before? We are not stuck with our genes. We can change the expression of our genes with every bite we take, step we take, thought we think. This is the concept of epigenetics.
I recently found out I have a copy of a gene mutation called MTHFR. Because I refer to this in many of my recipes as my motivation for eating the way I eat, I want to break it down in an easy, Cliffs notes kind of way. There are many websites out there that can explain it in depth (like this and this), but here are the basics:
An estimated 30-60% of the population has at least one copy of this gene. When you have MTHFR, your body cannot fully convert folic acid into methylfolate, the methylated form of folate, and some experts suggest that ANY folic acid consumed will block the absorption of folate – even that which you consume in whole foods. This is detrimental to our brain health, because neurotransmitters like serotonin, dopamine and norepinephrine need methylfolate for production.
Common health concerns sometimes associated with MTHFR include:
- ADHD, autism, mental illness (depression, anxiety, bipolar)
- Autoimmune disease/thyroid disorders
- Digestive issues
- Recurrent miscarriages
- Hormonal issues, like PCOS
- Blood clots, stroke, embolism
- And many many more (it’s a rabbit hole)